Deficiência de vitamina D e sua associação com a Síndrome Metabólica

Anderson da  Silva; Sandra José do Nascimento  Brito; Regicely Aline Brandão  Ferreira

doi:10.59171/nutrivisa-2017v4e9024

Autores

Anderson da Silva Secretaria Municipal de Saúde de Mauá
Sandra José do Nascimento Brito Sanfisio
Regicely Aline Brandão Ferreira Secretaria Municipal de Saúde de Mauá

DOI:

https://doi.org/10.59171/nutrivisa-2017v4e9024

Palavras-chave:

síndrome metabólica, vitamina D, deficiência, humanos

Resumo

A vitamina D possui como principal função regular a homeostase do cálcio. Sua síntese é estimulada com a exposição à luz solar e, também, pode ser obtida através da ingestão alimentar adequada. Diversas evidências têm demonstrado sua ligação com o desenvolvimento dos componentes da síndrome metabólica. Portanto, foi realizada uma revisão sistemática da literatura para reunir e aprimorar o conhecimento sobre o tema. Foram analisados estudos dos últimos 5 anos retrogradamente a partir de 01 de julho de 2010 na base de dados Pubmed (Medline) abrangendo todas as faixas etárias. Foram encontrados 13 artigos, dos quais 8 contemplavam os critérios de inclusão, sendo analisados e tendo seus principais achados descritos em um quadro. Todos os estudos demonstram que a deficiência de vitamina D está associada ao desenvolvimento de diversas alterações metabólicas do organismo, tais como obesidade, resistência à insulina, hiperglicemia, dislipidemia e hipertensão arterial, quadro que em conjunto configuram a síndrome metabólica. Após revisão sistemática dos estudos, concluiu-se que existe uma estreita relação entre a deficiência de vitamina D e a síndrome metabólica, contudo são necessários mais estudos para conhecer melhor todos os mecanismos envolvidos nesse processo.

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