Uma Revisão de literatura associando potenciais suplementações com intuito de reduzir a severidade da COVID-19

Gabriel Guimarães  Leão; Elizabete Helbig; Dulcinea  Blum Menezes

doi:10.59171/nutrivisa-2023v10e10887

Autores

Gabriel Guimarães Leão Universidade Federal de Pelotas, Faculdade de Nutrição, Pelotas, RS, Brasil. https://orcid.org/0000-0003-0295-592X
Elizabete Helbig Universidade Federal de Pelotas, Faculdade de Nutrição, Pelotas, RS, Brasil. https://orcid.org/0000-0001-7118-575X
Dulcinea Blum Menezes Universidade Federal de Pelotas, Campus Capão do Leão, Departamento de Microbiologia e Parasitologia, Capão do Leão, RS, Brasil. https://orcid.org/0000-0002-3484-8216

DOI:

https://doi.org/10.59171/nutrivisa-2023v10e10887

Palavras-chave:

Coronavirus, SARS-CoV-2, Nutrientes, Suplementos Nutricionais, Experimentação Humana Terapêutica

Resumo

Embora se reconheça o potencial patogênico de diferentes variantes de preocupação de SARS-CoV-2, o estado nutricional do paciente pode
corroborar para o agravamento do decurso da doença. O objetivo deste estudo foi relacionar conceitos dietéticos que favorecessem a menor
severidade em pacientes com COVID-19, considerando marcadores nutricionais relacionados, descritos na literatura, durante a pandemia de
COVID-19. Foi realizada revisão integrativa e qualitativa de dados da literatura especializada, acerca do tema, com o propósito de sintetizar os
principais resultados. Foram selecionados 19 artigos que atenderam aos critérios de inclusão e exclusão. Cerca de vitamina D3 5.000 a 10.000
UI/dia, durante 14 dias se mostrou suficiente para recuperação de sua deficiência, e melhora da condição agravada dos pacientes. A correção
do índice de vitamina C, através de suplementação de 100 mg/kg/dia durante de 5 a 15 dias foi corroborou para a redução da gravidade da
doença. Por meio de suplementações diárias de L-Glutamina 10g, durante 5 dias, e de ômega-3 1000 mg diariamente por 14 dias, observou-se
melhora de parâmetros bioquímicos de pacientes com COVID-19, além de ter sido observada maior sobrevida. Os dados aqui compilados de
diferentes estudos clínicos, demonstram que a correção dos índices séricos, através de suplementações, das vitaminas D3 e C e de L-Glutamina
e, Ômega-3 (EPA) e (DHA), no intuito de corrigir carências nutricionais, previamente apresentadas pelos pacientes avaliados, foram capazes
de colaborar significativamente com o melhor decurso de COVID-19. Foi possível associar a influência de potenciais suplementações para
a redução da severidade da doença.

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