Uma Revisão de literatura associando potenciais suplementações com intuito de reduzir a severidade da COVID-19

Gabriel Guimarães  Leão; Elizabete Helbig; Dulcinea  Blum Menezes

doi:10.59171/nutrivisa-2023v10e10887

Authors

Gabriel Guimarães Leão Universidade Federal de Pelotas, Faculdade de Nutrição, Pelotas, RS, Brasil. https://orcid.org/0000-0003-0295-592X
Elizabete Helbig Universidade Federal de Pelotas, Faculdade de Nutrição, Pelotas, RS, Brasil. https://orcid.org/0000-0001-7118-575X
Dulcinea Blum Menezes Universidade Federal de Pelotas, Campus Capão do Leão, Departamento de Microbiologia e Parasitologia, Capão do Leão, RS, Brasil. https://orcid.org/0000-0002-3484-8216

DOI:

https://doi.org/10.59171/nutrivisa-2023v10e10887

Keywords:

Coronavirus, SARS-CoV-2, Nutrients, Dietary Supplements, Therapeutic Human Experimentation.

Abstract

Although the pathogenic potential of different SARS-CoV-2 variants of concern is recognized, the patient's nutritional status may contribute to
the worsening of the disease course. The aim of this study was to relate dietary concepts that favored less severity in patients with COVID-19,
considering related nutritional markers, described in the literature, during the COVID-19 pandemic. An integrative and qualitative review of
data from the specialized literature on the subject was carried out, with the purpose of synthesizing the main results. Nineteen articles that met
the inclusion and exclusion criteria were selected. About 5,000 to 10,000 IU/day of vitamin D3, for 14 days, proved to be enough to recover
from the deficiency and improve the worsened condition of the patients. The correction of the vitamin C index, through supplementation of
100 mg/kg/day for 5 to 15 days, corroborated the reduction in the severity of the disease. Through daily supplements of L-Glutamine 10g, for
5 days, and omega-3 1000 mg daily for 14 days, an improvement in the biochemical parameters of patients with COVID-19 was observed,
in addition to having observed greater survival. The data compiled here from different clinical studies demonstrate that the correction of
serum indices, through supplements, of vitamins D3 and C and L-Glutamine and, Omega-3 (EPA) and (DHA), in order to correct nutritional
deficiencies, previously presented by the evaluated patients, were able to significantly collaborate with the best course of COVID-19. It was
possible to associate the influence of potential supplements with the reduction of disease severity.

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