Influência do estado nutricional e da composição corporal na predição de desfechos no tratamento quimioterápico em pacientes com câncer gástrico: uma revisão integrativa

Iago Matheus Alves de Holanda; Tamara Soares de Oliveira Araripe; Ingryd Fernandes de Macedo Soares

doi:10.52521/nutrivisa.v12i1.15952

Authors

Iago Matheus Alves de Holanda Universidade Estadual do Ceará, Fortaleza-CE, Brasil https://orcid.org/0009-0007-3342-7245
Tamara Soares de Oliveira Araripe Universidade Estadual do Ceará, Fortaleza-CE, Brasil https://orcid.org/0000-0002-8094-7872
Ingryd Fernandes de Macedo Soares Universidade Estadual do Ceará, Fortaleza-CE, Brasil https://orcid.org/0000-0001-8077-6463

DOI:

https://doi.org/10.52521/nutrivisa.v12i1.15952

Keywords:

gastric cancer; nutritional status; body composition; antineoplastic agents; integrative review.

Abstract

This study aims to investigate the influence of nutritional status and body composition on the prediction of clinical outcomes in patients with gastric cancer undergoing chemotherapy, through an integrative literature review. The research was conducted in the PubMed, Medline, and LILACS databases. Inclusion criteria encompassed articles published in the last ten years, available in Portuguese, English, or Spanish. Case reports, conference abstracts, opinion reviews, and articles without full-text availability were excluded. Nine studies were included, covering populations from different countries, which evaluated nutritional and body composition parameters using tools such as the Prognostic Nutritional Index (PNI), Nutritional Risk Index (NRI), and Computed Tomography (CT). The results demonstrated that low nutritional indices and body composition changes, such as reduced muscle mass, sarcopenia, and sarcopenic obesity, are associated with higher toxicity and worse overall survival. It is concluded that nutritional status and body composition can influence and serve as important predictors of clinical outcomes in gastric cancer patients undergoing chemotherapy. Integrating nutritional status and body composition assessments is essential for developing a better care plan for these patients.

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