Efeitos isolados e combinados da suplementação de flavonoides e exercício físico frente ao perfil bioquímico e oxidativo

David Michel de  Oliveira; Daniel dos  Santos

doi:10.17648/nutrivisa-vol-3-num-3-i

Autores

David Michel de Oliveira Universidade Federal de Goiás
Daniel dos Santos Universidade de Franca

DOI:

https://doi.org/10.17648/nutrivisa-vol-3-num-3-i

Palavras-chave:

flavonoides, exercícios físicos, terapêutica, perfil bioquímico, oxidativo

Resumo

O estudo teve como objetivo analisar e discutir criticamente trabalhos sobre os efeitos da suplementação isolada e combinada de flavonoides com o exercício físico no perfil bioquímico e oxidativo. Nesta revisão de literatura, foram selecionados artigos originais encontrados em bibliotecas virtuais relevantes sobre o tema em questão. A revisão sistemática demonstrou que os flavonoides promovem efeitos hipolipemiantes, hipoglicêmicos e aumentam as defesas antioxidantes, entretanto, não existe um consenso sobre seus mecanismos. Já está bem estabelecido que o exercício físico promove efeitos metabólicos benéficos no perfil bioquímico e oxidativo, entretanto, as variáveis modelo, volume e intensidade interferem na magnitude dos resultados. Na combinação da suplementação de flavonoides com exercícios físicos, acredita-se que possa existir efeito potencial sinérgico, tanto no controle bioquímico, quanto no aumento de defesas antioxidantes ocasionados pelos flavonoides, podendo ser uma associação terapêutica interessante no tratamento de doenças cardiometabólicas. Embora diversos estudos confirmem tais efeitos, ainda existem muitas discussões sobre os mecanismos de ação dos flavonoides cítricos e sua combinação com o exercício físico, sendo que as maiorias dos estudos são realizados em modelo experimental ou in vitro. Portanto, são necessárias mais investigações referentes à suplementação associada ao exercício físico com protocolos padronizados em humanos.

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