The treatments of madness and the history of antipsychotic agents

Authors

DOI:

https://doi.org/10.59487/2965-1956-2-10915

Keywords:

Psychotic Disorders, History of medicine, Antipsychotic Agents, Psychiatric Somatic Therapies

Abstract

Objective: Review the history of interventions on madness, focusing on the Ancient Age, Middle Ages, Modern Age and Contemporary Age, and present it as an introductory text to the study of the treatment of psychoses. Development: Madness, interpreted in this text as psychosis, has been studied since the Ancient Age, initially interpreted as a phenomenon of divine influence, followed by the theory of humors, which lasted from the classical greek period until the Enlightenment, after which Moral Treatment and treatments of an asylum nature were introduced. From the 20th century onwards, biological therapies began, such as convulsive therapy, and, in the second half of the century, the first antipsychotics appeared. Thus, throughout history, several explanations and treatments have been formulated. In this paper, we discuss part of those theories and therapies, from antiquity to contemporaneity, with the exception of the various psychotherapeutic modalities. Final considerations: Although not all knowledge is sustained over the years, part of it is maintained and resignified.

Downloads

Download data is not yet available.

References

Dalgalarrondo P. Psicopatologia e semiologia dos transtornos mentais. 3a ed. Porto Alegre: Artmed; 2019.

Rezende JM, Moraes VA, Perini GE. Seara de Asclépio: uma visão diacrônica da medicina. 2nd ed. Goiânia: Editora UFG; 2018.

Reinaldo AMS, Santos RLF. Religião e transtornos mentais na perspectiva de profissionais de saúde, pacientes psiquiátricos e seus familiares. Saúde debate [Internet]. 2016;40(110):162–171. Available from: https://doi.org/10.1590/0103-1104201611012

Rosen G. The Mentally Ill and the Community in Western and Central Europe During the Late Middle Ages and the Renaissance. Journal of the History of Medicine and Allied Sciences. 1964;19(4):377-388

Grant M. Dietetic responses in Galen to madness. Classical Bulletin. 2000;76:61-70.

Aucoin M, LaChance L, Cooley K, et al. Diet and Psychosis: A Scoping Review. Neuropsychobiology. 2020;79(1):20-42.

Laukkanen T, Laukkanen J, Kunustsor S. Sauna Bathing and Risk of Psychotic Disorders: A Prospective Cohort Study. Medicine Principals and Practice. 2018;27(6):562-569

Van Os J, Kenis G, Rutten B. The environment and schizophrenia. Nature. 2010;468(7321):203-212

Pessotti I. Sobre a teoria da loucura no século XX. Temas psicol.[Internet]. 2006 [citado 2023 Maio 15];14(2):113-123. Disponível em: http://pepsic.bvsalud.org/scielo.php?script=sci_arttext&pid=S1413-389X2006000200002 &lng=pt.

Amarante P. Saúde mental, políticas e instituições: programa de educação a distância. Rio de Janeiro: Fiotec/Fiocruz EAD/Fiocruz; 2003.

Conselho Federal de Psicologia, Mecanismo Nacional de Prevenção e Combate à Tortura, Procuradoria Federal dos Direitos do Cidadão, et al. Relatório da Inspeção Nacional em Comunidades Terapêuticas [Internet]. Brasília: CFP; 2018 [cited 2023 May 15]. Available from: https://site.cfp.org.br/publicacao/relatorio-da-inspecao-nacional-em-comunidades-terapeuticas/

Austin SC, Stolley PD, Lasky T. The history of malariotherapy for neurosyphilis: Modern parallels. JAMA. 1992;268(4):516-519.

Tierney J. Egas Moniz and the Origins of Psychosurgery: A Review Commemorating the 50th Anniversary of Moniz's Nobel Prize. Journal of the History of the Neurosciences. 2010;9(1):22-36.

Mahoney D, Green A. Psychosurgery: History of the Neurosurgical Management of Psychiatric Disorders. World Neurosurgery. 2020;137:327-334.

Fink M. Convulsive therapy: a review of the first 55 years. Journal of Affective Disorders. 2001;63(1):1-15

Baran B, Bitter I, Ungvari G, et al. The birth of convulsive therapy revisited: A reappraisal of László Meduna's first cohort of patients. Journal of Affective Disorders. 2012;136(3):1179-1182.

Delay J, Deniker P, Harl J. Utilisation en thérapeutique psychiatrique d'une phénothiazine d'action centrale élective. Annales médico-psychologiques. 1952;110(1):112-117.

Ban T. Fifty years chlorpromazine: a historical perspective. Neuropsychiatric disease and treatment. 2007;3(4):495-500.

Crow T. Molecular pathology of schizophrenia: more than one disease process?. Britsh Medical Journal. 1980;280(6207):66-68.

Hirsch L, Yang J, Bresee L, et al. Second-Generation Antipsychotics and Metabolic Side Effects: A Systematic Review of Population-Based Studies. Drug Safety. 2017;40(9):771-781.

Preda A, Shapiro B. A safety evaluation of aripiprazole in the treatment of schizophrenia. Expert Opinion on Drug Safety. 2020;19(12):1529-1538.

Azorin JM, Simon N. Dopamine Receptor Partial Agonists for the Treatment of Bipolar Disorder. Drugs. 2019;79(15):1657-1677.

Braslow J, Marder S. History of Psychopharmacology. Annual review of clinical psychology. 2019;7(15):25-50

Kane J, Honigfeld G, Singer J, et al. Clozapine in treatment-resistant schizophrenics. Psychopharmacology Bulletin. 1988;24(1):62-67.

Tailape H, Mittendorfer-Rutz E, Alexanderson K, et al. Antipsychotics and mortality in a nationwide cohort of 29,823 patients with schizophrenia. Schizophrenia Research. 2018;197:274-280.

Published

2023-10-23

How to Cite

1.
Pinto JP, Gaspar DM, Barroso NSC. The treatments of madness and the history of antipsychotic agents. Dialog Interdis Psiq S Ment [Internet]. 2023 Oct. 23 [cited 2024 Nov. 21];2(2):e10915. Available from: https://revistas.uece.br/index.php/dipsm/article/view/10915