ESTRESSE OXIDATIVO E ANTIOXIDANTES NO DE SÊMEN DE PEIXES
Palavras-chave:
Criopreservação, EROs, estresse oxidativo, antioxidantesResumo
Danos causados pelo processo de criopreservação, como o estresse oxidativo, levam a produção excessiva de EROS, podendo comprometer a fertilidade. Neste sentido, diversos antioxidantes vêm sendo adicionados aos diluentes de congelação de sêmen com o objetivo de minimizar os efeitos deletérios causados pelos radicais livres. Assim, esta revisão tem como objetivo debater os principais aspectos relacionados aos danos causados ao sêmen durante o processo de criopreservação, e o efeito do uso de antioxidantes sobre a viabilidade espermática de peixes.
Referências
AGARWAL, A.; SALEH, R.A. Role of oxidants in male infertility: rationale, significance, and treatment. Urologic Clinics of North America, v.29, n.4, p. 817-827, 2002.
AGARWAL, A.; PRABAKARAN, S.A.; SAID, T.M. Prevention of oxidative stress injury to sperm. Journal of Andrology, v.26, n.6, p.654-660, 2005.
AITKEN, R.J.; BAKER, M.A. Oxidative stress and male reproductive biology. Reproduction, Fertility and development, v.16, n.5, p.581-588, 2004.
AITKEN, R.J.; BENNETTS, L. Reactive oxygen species: friend or foe. In: DE JONGE, C.J.; BARRATT, C.L.R. The Sperm Cell: Production, maturation, fertilization, regeneration. New York:Cambrige University Press, p.170-193, 2006.
AMBROSINI, G.; ANDRISANI, A.; POUCU, E.; REBELLATO, E.; REVELLI, A.;
CASERTA, D.; COSMI, E.; MARCI, R.; MOSCARINI, M. Oocytes cryopreservation: state of art. Reproductive toxicology, v.22, n.2, p.250-262, 2006.
ARAMLI, M.S.; GOLSHAHI, K.; NAZARI, R.M.; GOLPOUR, A.; ARAMLI, S.
Influence of Glutamine Supplementation on Motility and Fertilization Success of Frozen– Thawed Persian Sturgeon (Acipenser persicus) Sperm. Reproduction in domestic animals, v.51, n.4, p.474-477, 2016.
ARMSTRONG, J.S.; RAJASEKARAN, M.; CHAMULITRAT, W.; GATTI, P.;
HELLSTROM, W.J.; SIKKA Characterization of reactive oxygen species induced effects on human spermatozoa movement and energy metabolism. Free Radical Biology and Medicine, v.26, n.7, p.869-880, 1999.
AURICH, C. Factors affecting the plasma membrane function of cooled-stored stallion spermatozoa. Animal Reproduction Science, v.89, n.1, p.65-75, 2005.
BAILEY, J.L.; BILODEAU, J.F.; CORMIER, N. Semen cryopreservation in domestic animals: a damaging and capacitating phenomenon. Journal of andrology, v.21, n.1, p.1-7, 2000.
BAKER, M.A.; AITKEN, R.J. The importance of redox regulated pathways in sperm cell biology. Molecular and cellular endocrinology, v.216, n.1, p.47-54, 2004.
BALL, B.A.; MEDINA, V.; GRAVANCE, C.G.; BAUMBER, J. Effect of antioxidants on preservation of motility, viability and acrosomal integrity of equine spermatozoa during storage at 5 C. Theriogenology, v.56, n.4, p.577-589, 2001.
BALL, B.A. Oxidative stress, osmotic stress and apoptosis: impacts on sperm function and preservation in the horse. Animal Reproduction Science, v.107, n.3, p.257-267, 2008.
BAUMBER, J.; BALL, B.A.; GRAVANCE, C.G.; MEDINA, V.; DAVIES-MOREL,
M.C. The effect of reactive oxygen species on equine sperm motility, viability, acrosomal integrity, mitochondrial membrane potential and membrane lipid peroxidation. Journal of andrology, v.21, n.6, p.895-902, 2000.
BAUMBER, J.; VO, A.; SABEUR, B.A. Generation of reactive oxygen species by equine neutrophils and their effect on motility of equine spermatozoa. Theriogenology, v.57, n.3, p.1025-1033, 2002.
BAUMBER, J.; BALL, B.A.; LINFOR, J.J. Assessment of the cryopreservation of equine spermatozoa in the presence of enzyme scavengers and antioxidants. American journal of veterinary research, v.66, n.5, p.772-779, 2005.
BAUST, J.G. The management of mammalian cells at low temperature. Cell Preservation, Technology, v.6, n.2, p.111-112, 2008.
BILODEAU, J.F.; CHATTERJEE, S.; SIRARD, M.A.; GAGNON, C. Levels of
antioxidant defenses are decreased in bovine spermatozoa after a cycle of freezing and thawing. Molecular reproduction and development, v.55, n.3, p.282-288, 2000.
BILODEAU, J.F.; BLANCHETTE, S.; GAGNON, C.; SIRARD, M.A. Thiols prevent
H2O2ˉ mediated loss of sperm motility in cryopreserved bull semen. Theriogenology, v.56, n.2, p.275-286, 2001.
BILODEAU, J.F.; BLANCHETTE, S.; CORMIER, N.; SIRARD, M.A. Reactive oxygen
species-mediated loss of bovine sperm motility in egg yolk Tris extender: protection by pyruvate, metal chelators and bovine liver or oviductal fluid catalase. Theriogenology, v.57, n.3, p.1105-1122, 2002.
BRÉQUE, C.; SURAI, P.; BRILLARD, J.P. Roles of antioxidants on prolonged storage of avian spermatozoa in vivo and in vitro. Molecular Reproduction and Development, v.66, n.3, p.314-323, 2003.
BUCAK, M.N.; ATESSAHIN, A.; YÜCE, A. Effect of anti-oxidants and oxidative stress parameters on ram semen after the freeze-thawing process [Corrigendum: 2008 June, v.77, issue 1, p.89.]. Small ruminant research, 2008.
BUCAK, M.N.; TUNCER, P.B.; SARIÖZKAN, S.; ULUTAR, P.A. Comparison of the
effects of glutamine and an amino acid solution on post-thawed ram sperm parameters, lipid peroxidation and anti-oxidant activities. Small Ruminant Research, v.81, n.1, p.13-17, 2009a.
BUCAK, M.N.; SARIÖZKAN, S.; TUNCER, P.B.; ULUTAS, P.A.; AKÇADA, H.I.
Effect of antioxidants on microscopic semen parameters, lipid peroxidation and antioxidant activities in Angora goat semen following cryopreservation. Small Ruminant Research, v.81, n.2, p.90-95, 2009b.
CABRITA, E.; MA S.; DIOGO, P.; MARTÍNEZ-PÁRAMO, S.; SARASQUETE, C.;
DINIS, M.T. The influence of certain aminoacids and vitamins on post-thaw fish sperm motility, viability and DNA fragmentation. Animal reproduction science, v.125, n.1-4, p.189-195, 2011.
CÂMARA, D.R.; GUERRA, M.M.P. Refrigeração e criopreservação do sêmen ovino: danos inerentes à técnica e influência da suplementação do meio com antioxidantes sobre a qualidade espermática. Revista Brasileira de Reprodução Animal, v.35, n.1, p.33-40, 2011.
CAROLSFELD J.; GODINHO, H.P.; ZANIBONI FILHO, E.; HARVEY, B.J.
Cryopreservation of sperm in Brazilian migratory fish conservation. Journal of Fish Biology, v.63, p.472-481, 2003.
CIERESZKO, A.; DABROWSKI, K. Sperm quality and ascorbic acid concentration in rainbow trout semen are affected by dietary vitamin C: an across-season study. Biology of Reproduction, v.52, p.982-988, 1995.
CIERESZKO A.; DABROWSKI, K.; KUCHARCZYK, D.; DOBOSZ, S.; GORYCZKO,
K.; GLOGOWSKI, J. The presence of uric acid, an antioxidative substance, in fish seminal plasma. Fish Physiology and Biochemistry, v.21, p.313-315, 1999.
ÇOYAN, K.; BASPINAR, N.; BUCAK, M.N.; AKALIN, P.P.; ATAMAN, M.B.; ÖMÜR, A.D.; GÜNGÖR, S.; KÜÇÜKGÜNAY, S.; ÖZKALP, B.; SARIÖZKAN, S. Influence of
methionine and dithioerythritol on sperm motility, lipid peroxidation and antioxidant capacities during liquid storage of ram semen. Research in veterinary science, v.89, n.3, p.426-431, 2010.
CRUZAT, V.F.; PETRY, E.R.; TIRAPEGUI, J. Glutamina: aspectos bioquímicos, metabólicos, moleculares e suplementação. Revista Brasileira de medicina do Esporte, v.15, n.5, p.392-397, 2009.
DE GRAAF, S.P.; EVANS, G.; GILLAN, L.; GUERRA, M.M.P.; MAXWELL, W.M.C.;
O’BRIEN, J.K. The influence of antioxidant, cholesterol and seminal plasma on the in vitro quality of sorted and non-sorted ram spermatozoa. Theriogenology, v.67, n.2, p.217- 227, 2007.
DE MERCADO, E.; HERNANDEZ, M.; SANZ, E.; RODRIGUEZ, A.; GOMEZ, E.;
VAZQUEZ, J.M. MARTINEZ, E.A.; ROCA, J. Evaluation of l-glutamine for cryopreservation of boar spermatozoa. Animal Reproduction Science, v.115, n.1, p.149- 157, 2009.
DURU, N.K.; MORSHEDI, M.; OEHNINGER, S. Effects of hydrogen peroxide on DNA and plasma membrane integrity of human spermatozoa. Fertility and Sterility, v.74, n.6, p.1200-1207, 2000.
EL-SHESHTAWY, R.I.; EL-SISY, G.A.; EL-NATTAT, W.S. Use of selected amino acids to improve buffalo bull semen cryopreservation. Global Veterinária, v.2, n.4, p.146-150, 2008.
GADEA, J.; GARCIA-VÁZQUEZ, F.; GUMBAO, D.; RODRÍGUEZ, F.A.; E MATÁS,
C. Addition of reduced glutathione to freezing medium improved the sperm functionality of thawed boar spermatozoa. Reproduction, fertility and development, v.17, n.2, p.192- 193, 2004.
GADEA, J.; GARCÍA‐VAZQUEZ, F.; MATÁS, C.; GARDÓN, J.C.; CÁNOVAS, S.E.;
GUMBAO, D. Cooling and freezing of boar spermatozoa: supplementation of the freezing media with reduced glutathione preserves sperm function. Journal of Andrology, v.26, n.3, p.396-404. 2005.
HAGEDORN, M.; MCCARTHY, M.; CARTER, V.L.; MEYERS, S.A. Oxidative stress in
zebrafish (Danio rerio) sperm. PloS One, v.7, n.6, p.39397, 2012.
JAIN, J.K.; PAULSON, R.J. Oocyte cryopreservation. Fertility and Sterility, v.86, n.4, p.1037-1046, 2006.
JOSHI, A.; BAG, S.; NAQVI, S.M.K.; SHARMA, R.C.; MITTAL, J.P. Effect of post-
thawing incubation on sperm motility and acrosomal integrity of cryopreserved Garole ram semen. Small Ruminant Research, v.56, n.1, p.231-238, 2005.
KLEDMANEE, K.; TAWEEDET, S.; THAIJONGRUK, P.; CHANAPIWAT, P.;
KAEOKET, K. Effect of L-cysteine on chilled carp (Cyprinus carpio) semen qualities. The Thai Journal of Veterinary Medicine, v.43, n.1, p.91-97, 2013.
KOPEIKA, J.; KOPEIKA, E.; ZHANG, T.; RAWSON, D.M.; HOLT, W.V. Detrimental
effects of cryopreservation of loach (Misgurnus fossilis) sperm on subsequent embryo development are reversed by incubating fertilised eggs in caffeine. Cryobiology, v.46, n.1, p.43-52, 2003.
KRZYZOSIAK, J.; EVENSON, D.; PITT, C.; JOST, L.; MOLAN, P.; VISHWANATH,
R. Changes in susceptibility of bovine sperm to in situ DNA denaturation during prolonged incubation at ambient temperature under conditions of exposure to reactive oxygen species and nuclease inhibitor. Reproduction, Fertility and Development, v.12, n.6, p.251-261, 2001.
KUNDU, C.N.; DAS, K.; MAJUMDER, G.C. Effect of amino acids on goat cauda epididymal sperm cryopreservation using a chemically defined model system. Cryobiology, v.42, n.1, p.21-27, 2001.
KUTLUYER, F.; KAYIM, M.; ÖĞRETMEN, F.; BÜYÜKLEBLEBICI, S.; TUNCER, P.
B. Cryopreservation of rainbow trout Oncorhynchus mykiss spermatozoa: Effects of extender supplemented with different antioxidants on sperm motility, velocity and fertility. Cryobiology, v.69, p.462-466, 2014.
LAHNSTEINER F. The role of free amino acids in semen of rainbow trout Oncorhynchus mykiss and carp Cyprinus carpio. Journal of Fish Biolology, v.75, p.816-833, 2009.
LAHNSTEINER, F.; MANSOUR, N. A comparative study on antioxidant systems in semen of species of the Percidae, Salmonidae, Cyprinidae, and Lotidae for improving semen storage techniques. Aquaculture, v.307, p.130-140, 2010.
LAHNSTEINER, F.; MANSOUR, N.; PLAETZER, C. Antioxidant systems of brown trout (Salmo trutta f. fario) semen. Animal Reproduction Science, v.119, p.314-321, 2010.
LAHNSTEINER, F.; MANSOUR, N.; KUNZ, F.A. The effect of antioxidants on the quality of cryopreserved sêmen in two salmonid fish, the brook trout (Salvelinus fontinalis) and the rainbow trout (Oncorhynchus mykiss). Theriogenology, v.76, p.882-890, 2011.
LI, P.; XI, M.D.; DU, H.; QIAO, X.M.; LIU, Z.G.; WEI, Q.W. Antioxidant
supplementation, effect on post‐thaw spermatozoa function in three sturgeon species. Reproduction in Domestic Animals, v.53, n.2, p.287-295, 2017.
LINDEBERG, H.; KURTEN, A.; KOSKINEN, E.; KATILA, T. Freezing of stallion
semen with addition of glycine betaine. Transboundary and Emerging Diseases, v.46, n.2, p.87-90, 1999.
LUBERDA, Z. The role of glutathione in mammalian gametes. Reproductive Biology, v.5, n.1, p.5-17, 2005.
MAIA, M.S.; BICUDO, S.D. Radicais livres, antioxidantes e função espermática em mamíferos: uma revisão. Revista Brasileira de Reprodução Animal, v.33, n.4, p.183-193, 2009.
MANSOUR, N.; MCNIVEN M.A.; RICHARDSON, G.F. The effect of dietary supplementation with blueberry, α-tocopherol or astaxanthin on oxidative stability of Artic char (Salvelinus alpinus) semen. Theriogenology, v.66, p.373-382, 2006.
MARTÍNEZ-PÁRAMO, S.; DIOGO, P.; DINIS, M.T.; HERRÁEZ, M.P.;
SARASQUETE, C.; CABRITA, E. Incorporation of ascorbic acid and α-tocopherol to the extender media to enhance antioxidant system of cryopreserved sea bass sperm. Theriogenology, v.77, n.6, p.1129-1136, 2012.
MARTÍNEZ-PÁRAMO, S.; DIOGO, P.; DINIS, M. T.; SOARES, F.; SARASQUETE, C.;
CABRITA, E. Effect oftwo sulfur-containing amino acids, taurine and hypotaurine in European sea bass (Dicentrarchus labrax) sperm cryopreservation. Cryobiology, v.66, p.333-338, 2013.
MAZUR, P.; LEIBO, S.P.; SEIDEL, J.R.G.E. Cryopreservation of the germplasm of animals used in biological and medical research: importance, impact, status, and future directions. Biology of reproduction, v.78, n.1, p.2-12, 2008.
MICHAEL, A.J.; ALEXOPOULOS, C.; PONTIKI, E.A.; HADJIPAVLOU-LITINA, D.J.;
SARATSIS, P.; VERVERIDIS, H.N.; BOSCOS, C.M. Effect of antioxidant supplementation in semen extenders on semen quality and reactive oxygen species of chilled canine spermatozoa. Animal Reproduction Science, v.112, n.1, p.119-135, 2009.
NORDBERG, J.; ARNÉR, E.S.J. Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radical Biology and Medicine, v.31, n.11, p.1287- 1312, 2001.
ÖĞRETMEN, F.; İNANAN, B.E.; KUTLUYER, F.; KAYIM, M. Effect of semen
extender supplementation with cysteine on postthaw sperm quality, DNA damage, and fertilizing ability in the common carp (Cyprinus carpio). Theriogenology, v.83, n.9, p.1548-1552, 2015.
PEGG, D.E. Cryopreservation of vascular endothelial cells as isolated cells and as monolayers. Cryobiology, v.44, n.1, p.46-53, 2002.
PEGG, D.E. Principles of cryopreservation. Cryopreservation and Freeze-drying Protocols, New Jersey: 2a ed., Humana Press, p.39-57, 2007.
PEÑA, A.I.; BARRIO, F.; QUINTELA, L.A.; HERRADON, P.G. Proline and glycine
betaine in a diluent for freezing canine spermatozoa. Reproduction in Domestic Animals, v.33, n.1, p.5-9, 1998.
PEÑA, F.J.; RODRÍGUEZ MARTÍNEZ, H.; TAPIA, J.A.; ORTEGA FERRUSOLA, C.;
GONZALEZ FERNANDEZ, L.; MACIAS GARCIA, B. Mitochondria in mammalian sperm physiology and pathology: a review. Reproduction in Domestic Animals, v.44, n.2, p.345-349, 2009.
PERIS, S.I.; MORRIER, A.; DUFOUR, M.; BAILEY, J.L. Cryopreservation of ram semen facilitates sperm DNA damage: relationship between sperm andrological parameters and the sperm chromatin structure assay. Journal of Andrology, v.25, n.2, p.224-233, 2004.
ROCA, J.; GIL, M.A.; HERNANDEZ, M.; PARRILLA, I.; VAZQUEZ, J.M.;
MARTINEZ, E.A. Survival and fertility of boar spermatozoa after freeze‐thawing in extender supplemented with butylated hydroxytoluene. Journal of Andrology, v.25, n.3, p.397-405, 2004.
SAROSIEK, B.; DRYL, K.; KUCHARCZYK, D.; ŻARSKI, D.E.; KOWALSKI, R.K.
Motility parameters of perch spermatozoa (Perca fluviatilis L.) during short-term storage with antioxidants addition. Aquaculture international, v.22, n.1, p.159-165, 2014.
SIKKA, S.C. Oxidative stress and role of antioxidants in normal and abnormal sperm function. Frontiers Bioscience, v.1, p.78-86, 1996.
SIKKA, S.C. Role of oxidative stress and antioxidants in andrology and assisted reproductive technology. Journal of Andrology, v.25, p.5-18, 2004.
SILVA, E.C.B.; GUERRA, M.M.P. Terapias antioxidantes na criopreservação espermática. Revista Portuguesa de Ciências Veterinárias, v.107, p.143-149, 2012.
SŁOWIŃSKA, M.; NYNCA, J.; CEJKO, B.I.; DIETRICH, M.A.; HORVÁTH, Á.;
URBÁNYI, B.E.; CIERESZKO, A. Total antioxidant capacity of fish seminal plasma. Aquaculture, v.400, p.101-104, 2013.
STEJSKAL, K.; SVOBODOVA, Z.; FABRIK, I.; ADAM, V.; BEKLOVA, M.; RODINA,
M.; KIZEK, R. Content of cysteine, reduced and oxidized glutathione in spermatozoa of representatives of Acipenseriformes (Acipenser baerii and A. ruthenus) as well as teleosts (Perca fluviatilis and Sander lucioperca). Journal of Applied Ichthyology, v.24, n.4, p.519- 521, 2008.
THOMASSEN, R.; FARSTAD, W. Artificial insemination in canids: a useful tool in breeding and conservation. Theriogenology, v.71, n.1, p.190-199, 2009.
TIRELLI, M.; BASINI, G.; GRASSELLI, F.; BIANCO, F.; TAMANINI, C.
Cryopreservation of pig granulosa cells: effect of FSH addition to freezing medium. Domestic Animal Endocrinology, v.28, n.1, p.17-33, 2005.
TUNCER, P.B.; BUCAK, M.N.; BÜYÜKLEBLEBICI, S.; SARIÖZKAN, S.; YENI, D.;
EKEN, A.; GÜNDOĞAN, M. The effect of cysteine and glutathione on sperm and oxidative stress parameters of post-thawed bull semen. Cryobiology, v.61, n.3, p.303-307, 2010.
VAN OVERVELD, F.W.; HAENEN, G.R.; RHEMREV, J.; VERMEIDEN, J.P.; BAST,
A. Tyrosine as important contributor to the antioxidant capacity of seminal plasma. Chemical-Biological Interactions, v.127, p.151–161, 2000.
VIVEIROS, A.T.M.; GODINHO, H.P. Sperm quality and cryopreservation of Brazilian freshwater fish species: a review. Fish Physiology and Biochemistry, v.35, p.137-150, 2009.
YAVAS, I.; BOZKURT, Y. Effect of different thawing rates on motility and fertilizing capacity of cryopreserved grass carp (Ctenopharyngodon idella) sperm. Biotechnology e Biotechnological Equipment, v.25, n.1, p.2254-2257, 2011.
YILDIZ, C.; BOZKURT, Y.; YAVAS, I. An evaluation of soybean lecithin as an alternative to avian egg yolk in the cryopreservation of fish sperm. Cryobiology, v.67, n.1, p.91-94, 2013.
WANG, X.; SHARMA, R.K.; GUPTA, A.; GEORGE, V.; THOMAS JR, A.J.;
FALCONE, T.; AGARWAL, A. Alterations in mitochondria membrane potential and oxidative stress in infertile men: a prospective observational study. Fertility and Sterility, v.80, p.844-850, 2003.
WATSON, P.F. The causes of reduced fertility with cryopreserved semen. Animal Reproduction Science, v.60, p.481-492, 2000.
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