Correlação entre o tipo de diabetes e rigidez arterial em pacientes adultos
DOI:
https://doi.org/10.70368/gecs.v1i1.12230Palavras-chave:
Rigidez arterial, Diabetes mellitus, Velocidade de onda de pulsoResumo
O diabetes mellitus (DM) pode induzir alterações em diferentes territórios arteriais e está associado ao desenvolvimento de consequências cardiovasculares. O mecanismo fisiopatológico subjacente a essas associações ainda não se encontra totalmente elucidado na literatura. No entanto, a rigidez arterial pode ser um caminho importante que liga o DM ao aumento da morbimortalidade cardiovascular. Este estudo objetiva verificar uma correlação entre o tipo de DM e rigidez arterial em pacientes diagnosticados na fase adulta. Noventa pacientes diabéticos com idade de 54,1 ± 9,3 anos foram alocados em 2 grupos: paciente com DM do tipo 1 (DM1; n=30) e tipo 2 (DM2; n=60). Foram avaliados os parâmetros antropométricos bem como a rigidez arterial através do método da velocidade de onda de pulso (VOP). Evidenciou-se um maior tempo de diabetes (p=0,007), menor massa corporal (p=0,034), IMC (p=0,007) e circunferência da cintura (p<0,001) nos pacientes com DM1 em comparação com os DM2. Observou-se maior índice de VOP (p<0,001) nos pacientes DM1 quando confrontados com os DM2. Analisando conjuntamente ou separado quanto à etiologia do DM, observou-se que quanto maior a concentração de HbA1c (>8%) maior foram os valores da VOP (p<0,05). Foi observada uma correlação positiva entre a VOP e a idade dos pacientes (r=0,89; p<0,001), duração do diabetes (r=0,71; p<0,001) e a HbA1c (r=0,70; p<0,001). Pessoas com DM1 apresentaram maior rigidez arterial quando comparados aos DM2, sendo que essas alterações foram associadas com uma maior disfunção metabólica nessa população.
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