Eficácia de probióticos na sintomatologia da constipação funcional em adultos: uma revisão integrativa
DOI:
https://doi.org/10.70368/gecs.v2i1.12153Palavras-chave:
constipação intestinal, microbiota, efetividade, probióticosResumo
O presente estudo objetiva revisar sobre a eficácia dos probióticos na melhora dos sintomas da constipação funcional em indivíduos saudáveis, identificando as cepas probióticas, dose e tempo de suplementação que sejam mais eficazes na redução dos sintomas. Foi realizada uma revisão integrativa com ensaios clínicos randomizados encontrados nas bases de dados da EBSCO, ScienceDirect, Scientific Electronic Library Online, Biblioteca Virtual em Saúde e Cochrane Library, com as seguintes expressões de busca: (functional constipation OR chronic constipation) AND (probiotics OR lactobacillus OR bifidobacterium OR Saccharomyces OR Streptococcus OR Enterococcus OR Bacillus coagulans OR Bacillus clausii OR lactococcus). Dez ensaios clínicos randomizados foram selecionados. Bacillus coagulans Unique IS2 e Lactobacillus reuteri DSM 17938 parecem melhorar diversos parâmetros da constipação, como sensação de evacuação incompleta, dor abdominal e ao evacuar, e Lactobacillus plantarum LRCC5193 parece melhorar a consistência da evacuação. Populações mais constipadas parecem ter maior tendência a apresentar melhora da constipação, com exceção as que apresentem maior tempo de trânsito colônico. Conclui-se que o efeito dos probióticos parece estar atrelado ao maior tempo de suplementação, tipo, dose e forma farmacêutica. Há necessidade de desenvolvimento de estudos mais controlados e de maior rigor científico.
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Copyright (c) 2024 Leticia Foglia Santucci, Alane Nogueira Bezerra
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