Aspectos anatomopatológicos de um granuloma fúngico em uma arara-canindé
Keywords:
Aspergillosis, Aspergillus sp, ringworm, psittacines, BrazilAbstract
The order Psittaciformes comprises primarily Neotropical birds, including the blue-and-yellow macaw (Ara
ararauna). Both in their natural habitat and under captive conditions, psittacines exhibit a high susceptibility to
infectious diseases, particularly those of fungal etiology. This article aims to describe a case of fungal granuloma
in a 22-year-old female blue-and-yellow macaw housed in a wildlife shelter. The bird was admitted for evaluation
due to a swelling in the right inguinal region with an undetermined duration of progression. Following cytological
findings suggestive of xanthoma, the mass was surgically excised and submitted for histopathological analysis.
Gross examination revealed a superficially desiccated core, largely encased by a firm, thickened wall.
Histopathological evaluation demonstrated subcutaneous tissue effacement by sclerotic connective tissue,
interspersed with aggregates of heterophils, epithelioid macrophages, and multinucleated giant cells. The
superficial material consisted of caseous necrotic debris containing numerous faintly basophilic, filamentous
structures. These were most prominently visualized using periodic acid-Schiff (PAS) staining and Grocott’s
methenamine silver (GMS) impregnation, which highlighted a delicate cell wall, distinct septations, and
dichotomous branching—morphological features consistent with fungal hyphae. These findings supported a
definitive diagnosis of a ruptured heterophilic granuloma with fungal etiology, most likely caused by Aspergillus
spp. Suboptimal husbandry conditions, overcrowding, and elevated environmental fungal load are known risk
factors for immunosuppression and the subsequent development of opportunistic mycoses.
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