Vol. 34 No. 4 (2024): Revista Ciência Animal
Artigos Originais

Histopathological characterization of splenic lesions in splenectomized dogs

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  • Filliphe Santos BARROS,
  • Eduardo Gomes DE PAULA,
  • Felipe Augusto Ruiz SUEIRO,
  • Paulo César JARK
Filliphe Santos BARROS
Dpto de Oncologia Clínica e Cirúrgica Veterinária, Universidade Brasil.
Eduardo Gomes DE PAULA
Universidade Brasil
Felipe Augusto Ruiz SUEIRO
Laboratório de Análises Clínicas VETPAT
Paulo César JARK
Universidade Brasil

Published 2024-12-30

Keywords

  • Histopathological characterization,
  • splenectomy,
  • hemangiossarcoma,
  • splenic lesion,
  • neoplasm

How to Cite

BARROS, F. S.; PAULA, E. G. D.; SUEIRO, F. . A. R.; JARK, P. C. Histopathological characterization of splenic lesions in splenectomized dogs. Ciência Animal, [S. l.], v. 34, n. 4, p. 50–60, 2024. Disponível em: https://revistas.uece.br/index.php/cienciaanimal/article/view/14716. Acesso em: 20 feb. 2026.
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

The spleen plays vital roles in the immune and hematopoietic systems of dogs. Splenic abnormalities are common and frequently diagnosed, requiring precise evaluations to determine the appropriate course of treatment. In veterinary medicine, there is no consensus on differentiating these alterations; therefore, a commonly used practice is total splenectomy followed by histopathological evaluation. Histopathological evaluation of a large number of spleen lesions can draw veterinarians' attention to the percentage of reactive or benign splenic lesions in dogs, guiding them to find new differentiation patterns for these lesions before performing splenectomy. This study reviewed 1,164 cases of splenic lesions in dogs between 2008 and 2018. The data reveal that 55.9% of the lesions are non-neoplastic, while 34.7% are malignant neoplasms, with splenic hemangiosarcoma (HSA) being prominent. Benign neoplasms represented 9.4% of the samples. The average age of the animals ranges from 9.7 to 10.5 years, depending on the type of lesion. Mixed-breed dogs are most affected, representing 25.6% of the cases. These results underscore the importance of histopathological evaluation in differentiating between benign and malignant lesions. Additionally, they suggest that many splenectomies could have been avoided with a better understanding of the characteristics of splenic lesions. These findings have significant implications for surgical decision-making, highlighting the need for a more careful and individualized approach to the treatment of splenic
lesions in dogs.

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