Subcutaneous fungal granuloma in an Leptodactylus vastus an local urban natural reserve
Published 2024-11-06
Keywords
- Amphibians,
- fungi,
- inflammation,
- mineralization
How to Cite

This work is licensed under a Creative Commons Attribution 4.0 International License.
Abstract
A granulomatous reaction is a chronic inflammation that forms masses or nodules. The objective of this study was to report the occurrence of a focal subcutaneous fungal granuloma in a L. vastus from an urban reserve in Ceará, Brazil. During monitoring of AMP, one specimen of L. vastus presented a subcutaneous botryoid nodule in the right palmar region. Cytological analysis revealed asteroid bodies, Splendori-Hoeppli reaction, macrophages, multinucleated giant cells, and degranulated eosinophils, spores, septate hyphae, and mineralization, which are compatible with a dimorphic fungal granuloma, requiring complementary techniques to confirm the specific agent.
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References
- AMPHIBIAWEB. Leptodactylus vastus. University of California, Berkeley, USA. Disponível
- em: https://amphibiaweb.org/amphibian/amph_index.html. Acesso em: 28 mai. 2024.
- BORGES, B.M.; RAMOS, R.B.C.; PREITE, N.W.; KAMINSKI, V.L.; ALVES DE CASTRO,
- P.; CAMACHO, M.; MAXIMO, M.F.; FILL, T.P.; CALICH, V.L.G.; TRAYNOR, A.M.;
- SARIKAYA-BAYRAM, Ö.; DOYLE, S.; BAYRAM, Ö.; DE CAMPOS, C.B.L.; ZELANIS,
- A.; GOLDMAN, G.H.; LOURES, F.V. Transcriptional profiling of a fungal granuloma reveals
- a low metabolic activity of Paracoccidioides brasiliensis yeasts and an actively regulated host
- immune response. Frontiers in Cellular and Infection Microbiology, v.13, n.1, p.1-27, 2023.
- BRAGA, R.R.; ELEUTÉRIO, B.K.N.; LIMA, R.C.S.; QUIRINO, T.F. Marked systemic
- necrotizing disease in a Leptodactylus vastus (Anura:Leptodactylidae) from an urban reserve
- in northeastern Brazil. Brazilian Journal of Veterinary Pathology, v.16, n.3, p.203–207,
- ELEUTÉRIO, B.K.N.; LIMA, R.C.S.; QUIRINO, T.F.; BRAGA, R.R. Parâmetros clínicos e
- fatores de influência em Leptodactylus vastus, Lutz, 1930 (Anura: Leptodactylidae) de
- uma reserva natural urbana em Fortaleza, Ceará. In: Anais do X Congresso Brasileiro de
- Herpetologia, 2023, Porto Seguro. [...]. Porto Seguro: SBH, 2023, p.548.
- FELIX-NASCIMENTO, G.; LUCENA, R.B.; FONSECA, C.F.; SILVA, I.J.S.; MORAES,
- C.C.N.; CARVALHO, C.A.C.; MOURA, G.J.B.; VIEIRA, F.M.; RIBEIRO, L.B.; OLIVEIRA,
- J.B. Mineral profile and histopathological findings in the liver of white-lipped frog
- (Leptodactylidae) from the morphoclimatic domain of the Caatingas, Brazil. Environ Science
- Pollution Research, v.31, n.1, p.10750–10765, 2024.
- FISCHER, J.R.; BROWN, R.G.; MILLER, A.M. Mycobacteriosis in Amphibians: Report of
- Two Cases in the Southeastern United States and a Review of the Literature. Journal of
- Zoo and Wildlife Medicine, v.40, n.3, p.568-578, 2009.
- GIBBONS, P.; WHITAKER, B.R.; CARPENTER, J.; MCDERMOTT, C.; KLAPHAKE, E.;
- SLADKY, K. Hematology and Biochemistry Tables. In: DIVERS, S.J.; STAHL, S. Mader’s
- Reptile and Amphibian Medicine and Surgery. Saint Louis: 3. ed., Elsevier, 2019. p.333–
- HASSAN, H.A.; MAJID, R.A.; RASHID, N.G.; NURADEEN, B.E.; ABDULKARIM, Q.H.;
- HAWRAMY, T.A.; RASHID, R.M.; FARRIS, A.B.; GUARNER, J.; HUGHSON, M.D.
- Eosinophilic granulomatous gastrointestinal and hepatic abscesses attributable to
- basidiobolomycosis and fasciolias: a simultaneous emergence in Iraqi Kurdistan. BMC
- Infectious Diseases, v.13, n.1, p.91-99, 2013.
- HUSSEIN, M.R. Mucocutaneous Splendore‐Hoeppli phenomenon. Journal of Cutaneous
- Pathology, v.35, n.11, p.979–988, 2008.
- JPC. The Joint Pathology Center. Conference 09, 2014 Case: 04 20141105:
- Chromoblastomycosis, ditch frog. Disponível em: https://www.askjpc.org/wsco/wsc_
- showcase2.php?id=VnVTejNDMHM0RURYd3Bnb0hwWjFLdz09. Acesso em: 28 mai. 2024.
- JUOPPERI, T.; KARLI, K.; DE VOE, R.; GRINDEM, C.B. Granulomatous Dermatitis in a
- Spadefoot Toad (Scaphiopus holbrooki). Veterinary Clinical Pathology, v.31, n.3, p.137–139,
- RUSH, H.G.; ANVER, M.R.; BENEKE, E.S. Systemic chromomycosis in Rana pipiens.
- Laboratory Animal Science, v.24, n.4, p.646–55, 1974.
- SANTOS, D.W.C.L.; VICENTE, V.A.; WEISS, V.A.; DE HOOG, G.S.; GOMES, R.R.;
- BATISTA, E.M.M.; MARQUES, S.G.; QUEIROZ-TELLES, F.; COLOMBO, A.L.;
- AZEVEDO, C.M.P.S. Chromoblastomycosis in an Endemic Area of Brazil: A Clinical-
- Epidemiological Analysis and a Worldwide Haplotype Network. Journal of Fungi, v.6, n.4,
- p.204-211, 2020.
- WILLERS, N.S.; LIMA, R.C.S.; CUNHA, W.P.C.; QUIRINO, T.F.; BRAGA, R.R. Influência
- de hemoparasitoses em perfil diferencial leucocitário da rã pimenta (Leptodactylus vastus)
- Lutz, 1930 (Anura: Leptodactylidae) de reserva urbana no Ceará. In: Anais do XII
- Encontro Nordestino de Grupos de Estudos de Animais Selvagens (ENGEAS), 2023, Areia.
- [...]. Areia: 2023.
- WILLIAMS, O.; FATIMA, S. Granuloma. In: StatPearls [Internet]. Treasure Island (FL):
- StatPearls Publishing, 2022. Disponível em: https://www.ncbi.nlm.nih.gov/books/NBK
- /. Acessado em: 28 mai. 2024.