Ketoprofen intoxication in dog
Keywords:
Dog, intoxication, ketoprofenAbstract
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in human and veterinary medicine because of their analgesic, antipyretic and anti-inflammatory properties, however, they are drugs frequently involved in small animal intoxications. Although its use is safe in dogs, there is a risk of promoting renal and gastrointestinal toxicity, and some authors have observed in this species digestive lesions with clinical manifestations that are noteworthy after the use of non-selective COX-2 NSAIDs, such as ketoprofen. Thus, the objective of this work is to report a case of ketoprofen intoxication in dogs.
References
ANDRADE, S.F. Manual de terapêutica Veterinária. 2a ed. São Paulo: Roca, 2002, 912p.
ISAACS, J.P. Adverse effects of non-steroidal anti-inflamatory drugs in the dog and cat. Australian Veterinary Practioner, v.26, n.4, p.180-186, 1996.
OSWEILER, G. D.; HOVDA, L. R; BRUTLAG, A. G.; LEE, J. A. Blackwell’s Five-Minute Veterinary Consult Clinical Companion: Small Animal Toxicology. 2ª ed. Blackwell Publishing, 2011. 888p.
PAPICH, M.G. An update on nonsteroidal anti-inflammatory drugs (NSAIDs) in Small Animals. Veterinary Clinical Small Animal, v.38, p.1243-1266, 2008.
SPINOSA, H.S.; GORNIAK, S L.; BERNARDI, M.M. Farmacologia aplicada à medicina veterinária, 4a ed. Rio de Janeiro: Guanabara Koogan, 2006. 897p.
SPINOSA, H.S.; GÓRNIAK, S.L.; PALERMO NETO, J. Toxicologia aplicada à medicina veterinária. Barueri, SP: Manole, 2008. 942p.
TALCOTT, P.A. Nonesteroidal Antiinflammatories. In: PETERSON, M.E., TALCOTT, P.A. Small Animal Toxicology. 2ª ed. Saint Louis: Saunders, 2006, p.902-928.