BONE AND PULMONARY METASTASIS FROM A MAMMARY ADENOSQUAMOUS CARCINOMA IN A BITCH
Schlagworte:
Dog, Mammary gland, Bone metastasis, Squamous metaplasiaAbstract
Mammary tumors are the most common in bitches, and bone and pulmonary metastases are not well described. Adenosquamous mammary carcinoma is a rare tumor that can be classified as a type of metaplastic tumor. This report describes the clinical and histopathological findings of this atypical presentation of mammary carcinoma in an 11-year-old, spayed, Poodle. Surgery was performed to remove malignant mammary nodules with a provisional diagnosis of carcinoma on cytologic examination. Thirteen months later, the dog returned showing left pelvic limb lameness that had persisted for 6 months prior to the consultation. The patient showed right pelvic limb lameness and a mass in the same limb. Radiographs of the affected limb revealed a pathological fracture in the femoral diaphysis and proliferation of the periosteum. After clinical staging, a left pelvic limb amputation was performed. A diagnosis of grade II adenosquamous mammary carcinoma was made through histopathology and immunohistochemistry. Although uncommon, bone and pulmonary metastases from mammary tumors, such as adenosquamous carcinoma, can be considered differential diagnoses for bony tumors. This report highlights the aggressive nature and significant metastatic potential of the adenosquamous carcinoma.
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