RESPOSTA METABÓLICA AO TRAUMA CIRÚRGICO

Autores

  • Sabrina Marin RODIGHERI Universidade Positivo (UP)
  • Felie Noleto de PAIVA Universidade Estadual Paulista (UNESP)
  • Andrigo Barboza DE NARDI Universidade Estadual Paulista (UNESP)

Palavras-chave:

Cirurgia, Metabolismo, Resposta inflamatória, Estresse cirúrgico

Resumo

Os efeitos do trauma cirúrgico no organismo, os quais são amplamente estudados pela medicina humana e veterinária, resultam em uma complexa resposta neuroendócrina e imunológica, desencadeadas para restabelecer a homeostase e preservar a vida. A resposta metabólica ao trauma é caracterizada pelo aumento da secreção de hormônios hipofisários, ativação do sistema nervoso simpático e secreção de citocinas pró-inflamatórias. Essa resposta tem por objetivo manter a perfusão tecidual, controlar a proliferação de microrganismos e mobilizar substratos para garantir a integridade das funções celulares e promover reparação tecidual. Diferentes fatores podem influenciar a intensidade da resposta do organismo ao trauma, incluindo magnitude e duração dos estímulos, enfermidades ou eventos traumáticos pré-existentes, protocolos anestésicos e técnicas cirúrgicas utilizadas. Respostas metabólicas exacerbadas ocasionam complicações pós-operatórias, tempo prolongado de recuperação dos pacientes e óbito. Através da identificação dos principais eventos relacionados à resposta metabólica ao trauma cirúrgico, é possível atuar de forma a reduzir os danos associados, melhorando a qualidade e minimizando os riscos do período pós-operatório. Sendo assim, este trabalho tem como objetivo apresentar uma revisão descrevendo a fisiopatologia e as consequências da resposta metabólica ao trauma cirúrgico, em suas diferentes formas e origens, no período perioperatório.

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Publicado

2022-11-17

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RODIGHERI, S. M. .; PAIVA, F. N. de .; DE NARDI, A. B. . RESPOSTA METABÓLICA AO TRAUMA CIRÚRGICO. Ciência Animal, [S. l.], v. 32, n. 1, p. 71–83, 2022. Disponível em: https://revistas.uece.br/index.php/cienciaanimal/article/view/9449. Acesso em: 24 jul. 2024.

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